食管鳞状细胞癌组织telomerase及PCNA的表达意义

时间：2020-10-06 13:51:59 药学毕业论文我要投稿

作者：李牧，曹学文，姜君威，杨永珠，张雁山
【关键词】食管癌
Expression of telomerase and PCNA protein in esophageal squamous cell carcinoma tissue and its significance
　　【Abstract】 AIM: To study the expression of telomerase and PCNA protein in four different pathological types of advanced esophageal cell cancer. METHODS: One hundred and twentysix cases with esophageal cancer of different pathological types were included in study by immunohistochemistry and the results were analyzed by SPSS 10.0. RESULTS: The positive rates of telomerase expression and PCNA were 60.0% (18/30) and 83.3% (25/30) in fungating type, 75.0% (21/28) and 78.5% (22/28) in constrictive type, 75.0% (24/32) and 15.6% (5/32) in ulcerative type and 44.4% (16/36) and PCNA 77.8% (28/36) in medullary type. Chisquare test was performed (telomerase χ2=378.829, P

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