姜黄素对代谢综合征大鼠ICAM

时间:2022-08-24 04:16:20 药学毕业论文 我要投稿
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姜黄素对代谢综合征大鼠ICAM

作者:陶正贤,龙明智,赵慧娟,谭晓,王迪斌,陶立翠
【关键词】 代谢综合征;细胞黏附分子;姜黄素;内皮功能障碍
  Effect of curcumin on ICAM1 and relative serum indexes in rats with metabolic syndrome
  【Abstract】AIM: To investigate the therapetutic effects of curcumin on metabolic syndrome (MS) in rats and the underlying mechanism. METHODS: Thirty SD male rats were randomly separated into 3 groups (n=10 in each one): control, model and curcumin groups. Rats in model and curcumin groups were treated with twokidneys oneclipped to induce renal hypertension and fed with a high fructose diet for 4 week to induce MS. Shamoperated rats were taken at random as noninfarction control. After intragastric administration of either curcumin (200 mg/kg